UNDERSTANDING POLYMORPHISM AND CRYSTALLISATION ISSUES IN THE PHARMACEUTICAL INDUSTRY

After an introduction the course will cover crystallisation of compounds (including hydrates and solvates), different methods of crystallisation, polymorphism, salts and cocrystals, crystallisation of chiral compounds and classical resolution, analytical methods for studying the solid state and will finish with some case studies. Real life practical examples will be used throughout the course to exemplify the different aspects of crystallisation and polymorphism.
The course will cover all aspects of the subject including crystallization of intermediates as well as final products. In addition, precipitations and amorphous solids will be covered and the differences between amorphous solids and crystalline solids will be discussed.

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Speakers: Dr John Studley