Assessment of Fc-mediated Functional Activity for the Development of Complex Biologics and Bioconjugates

2 months ago Posted By : User Ref No: WURUR204035 0
  • Image
  • TypeWebinar
  • Image
  • Location Online Event
  • Price
  • Date 23-01-2025
Webinar Title
Assessment of Fc-mediated Functional Activity for the Development of Complex Biologics and Bioconjugates
Event Type
Webinar
Webinar Date
23-01-2025
Last Date for Applying
23-01-2025
Location
Online Event
Organize and Presented By
Xtalks
Sponsored By
Abzena
Organizing/Related Departments
Xtalks Webinars
Organization Type
Company
WebinarCategory
Both (Technical & Non Technical)
WebinarLevel
All (State/Province/Region, National & International)
Related Industries

Research/Science

Biotechnology

Medical/Healthcare/Hospital

Location
Online Event

In this webinar, the expert speakers will review strategies for phase-appropriate assessment of Fc-mediated functional activity and present new developments for complex modalities.

The success of many cancer therapeutics lies in their ability to induce cytotoxicity by NK cells (antibody-dependent cellular cytotoxicity (ADCC)), phagocytosis (antibody-dependent cellular phagocytosis (ADCP)) and complement-dependent cytotoxicity (CDC) against specific targets; therefore, appropriate assessment is crucial before progressing a drug into the clinic.

Importantly, demonstrating the lack of unwanted effector functions is required for safety purposes. During this webinar, the expert speakers will consider the key aspects for developing successful Fc-mediated functional assays and will review the benefits and challenges of a panel of assay formats for different purposes.

They will also present options for choosing the most suitable target cell lines, effector cells and appropriate controls. Moreover, they will showcase studies on how rigorous data trending leads to reliable assays and how more complex formats, such as how real-time spheroid cytotoxicity assays contribute to understanding the mode of action and selecting the most promising lead.

Register for this webinar to obtain an overview of how Fc-mediated functions (or lack of) are essential to the success of biologic drugs and how best to evaluate these functions.

 

 

 

 

 

 

 

 

 

 

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Keywords: Cancer, Drug Development, Biologics, CRO, Oncology, Therapeutics, biotherapeutic, Therapeutic Areas, Biologics Manufacturing, Cell & Gene Therapies, Basic Research

Others Details

Life Sciences,Pharmaceutical,Drug Discovery & Development,Cell and Gene Therapy

Registration Fees
Free
Registration Ways
Website
Address/Venue
Online  Online 
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